Kv7.2/Kv7.3 agonist 1

Overview

Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally active agonist for KV7.2/7.3 channel ( KCNQ2/3 ) with an EC 50 of 1.03 μM. Kv7.2/Kv7.3 agonist 1 exhibits analgesic efficacy in mice chronic constriction injury (CCI) model and mice Streptozotocin ( HY-13753 )-induced diabetic peripheral neuropathic pain (DPNP) model, with ED 50 of 12.02 and 9.63 mg/kg.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-168214
• CAS No.: 2315450-35-0
• Molecular Formula: C14H14FN3O2
• Molecular Weight: 275.28
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source