PROTAC SMARCA2 degrader-31

Overview

PROTAC SMARCA2-degrader-36 is a PROTAC degrader of SMARCA2 , achieving a 99% degradation rate in H929 cells. It also exhibits degradative activity against SMARCA4 , but with relatively weaker efficacy. PROTAC SMARCA2-degrader-36 can inhibit cancer cell proliferation and may be used in research related to multiple myeloma. (Pink: SMARCA2 ligand ( HY-44012 ); Blue: VHL ligand ( HY-112078 ); Black: linker ( HY-W014125 )).

Application

Products | Products > Disease Areas > Multiple Myeloma | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-168234
• CAS No.: 2380274-45-1
• Molecular Formula: C48H65N9O6S
• Molecular Weight: 896.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source