PROTAC BRM/BRG1 degrader-1

Overview

PROTAC BRM/BRG1 degrader-1 (Example 253) is a PROTAC BRM/BRG1 degrader, with DC 50 of 10-100 nM for BRM, > 1 μM for BRG1. PROTAC BRM/BRG1 degrader-1 can be used for cancer research. (Pink: SMARCA2/BRM/BAF190B/SNF2L2 and SMARCA4/BRG1/BAF190A ligand ( HY-W539427 ); Blue: VHL ligand ( HY-168243 ); Black: linker ( HY-168244 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-168242
• CAS No.: 2724268-88-4
• Molecular Formula: C54H63N9O9S
• Molecular Weight: 1014.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source