5-HT6 inverse agonist 1

Overview

5-HT6 inverse agonist 1 (Compound 33) is an antagonist for 5-HT6 receptor with a K i of 23 nM and a K b of 6.62 nM. 5-HT6 inverse agonist 1 inhibits the 5-HT6R mediated Cdk5 and mTOR signaling pathway. 5-HT6 inverse agonist 1 reduces tactile hypersensitivity in spinal nerve ligation (SNL)-induced rat model.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-168333
• CAS No.: 2727088-38-0
• Molecular Formula: C22H22Cl2FN3O3S
• Molecular Weight: 498.40
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source