E0924G

Overview

E0924G is an orally active activator for PPARδ with EC 50 of 2.82 μM. E0924G promotes the upregulation of osteoprotegerin (OPG) with an EC 50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized (OVX) and age-related osteoporosis models.

Application

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Product Information

• Catalog No.: HY-168336
• CAS No.: 2909474-29-7
• Molecular Formula: C12H12N2O3
• Molecular Weight: 232.24
• Purity: 99.17%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (21.53 mM); Clear solution
• Availability: In-stock

Source

Original product source