9(10)-Nitrooleate

Overview

9 (10)-Nitrooleate (9(10)-Nitrated oleic acid) is an endogenous lipid signaling mediator with vasoprotective effects. 9 (10)-Nitrooleate enhances enzymatic activity and improves nitric oxide bioavailability by inducing phosphorylation of Akt and ERK1/2 , regulating the multi-site phosphorylation status of eNOS and optimizing its interaction with Hsp90 . 9 (10)-Nitrooleate also activates PPARα , PPARδ and PPARγ receptors, thereby regulating adipogenesis, glucose uptake and inflammation-related gene expression, and exhibits immunosuppressive effects by inhibiting neutrophil migration and cytokine secretion. 9 (10)-Nitrooleate is widely used in studies of sepsis and related inflammatory diseases.

Application

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Product Information

• Catalog No.: HY-168376
• CAS No.: 1092676-99-7
• Molecular Formula: C18H33NO4
• Molecular Weight: 327.46
• Purity: 99.98%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source