dBAZ2

Overview

dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC 50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol ( HY-47851 ); Black: linker ( HY-168450 ); pink: target protein ligand ( HY-168449 )). (Pink: BAZ2A and BAZ2B ligand ( HY-168449 ); Blue: VHL ligand ( HY-47851 ); Black: linker ( HY-168450 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-168448
• CAS No.: 3104449-57-9
• Molecular Formula: C54H64FN11O5S2
• Molecular Weight: 1030.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source