RIPK2-IN-6 (Compound 15a) is an inhibitor for RIPK , that inhibits the phosphorylation of RIPK2 , and thus inhibits the NF-κB and MAPK signaling pathways. RIPK2-IN-6 exhibits anti-inflammatory and anti-fibrotic activities in Dextran sodium sulfate ( HY-116282C )-induced mice colitis models.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > RIP kinase | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > p38 MAPK
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