GSK-3β inhibitor 24

Overview

GSK-3β inhibitor 24 (Compound 41) is a potent GSK-3β inhibitor with an IC 50 of 0.22 nM. GSK-3β inhibitor 24 increases GSK-3β phosphorylation at Ser9 site dose-dependently. GSK-3β inhibitor 24 inhibits the hyperphosphorylation of tau protein by decreasing the p-tau-Ser396 abundance. GSK-3β inhibitor 24 up-regulates β-catenin and neurogenesis-related markers (GAP43 and MAP-2). GSK-3β inhibitor 24 demonstrates remarkable anti-Alzheimer's disease (AD) effects.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > Tau Protein | Products > Signaling Pathways > β-catenin

Product Information

• Catalog No.: HY-168857
• CAS No.: 3069913-37-4
• Molecular Formula: C26H18N4O3
• Molecular Weight: 434.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source