Keap1-Nrf2-IN-25

Overview

Keap1-Nrf2-IN-25 (Compound 19) is a potent Keap1-Nrf2 inhibitor ( IC 50 of 0.55 μM) with Keap1 binding affinity ( K d of 0.50 μM). Keap1-Nrf2-IN-25 activates Nrf2 , reduces ROS and pro-inflammatory cytokines ( IL-1β , IL-6 ). Keap1-Nrf2-IN-25 exerts protective effects against DSS ( HY-116282 )-induced colitis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-168922
• CAS No.: 3100306-80-4
• Molecular Formula: C25H28N2O6S
• Molecular Weight: 484.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source