Paeoniflorin-6′-O-benzene sulfonate

Overview

Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 ( GRK2 ) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A , IL-17F , IFN-γ , TNF-α, IL-22 , IL-23 , CXCL2, CXCL3 and CXCL9 , alleviates Imiquimod ( HY-B0180 )-induced psoriasis in mouse model.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > G Protein-coupled Receptor Kinase (GRK) | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > JAK | Products > Signaling Pathways > STAT | Products > Signaling Pathways > CXCR | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-168971
• CAS No.: 1390658-79-3
• Molecular Formula: C29H32O13S
• Molecular Weight: 620.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source