Leptomycin B

Overview

Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle.

Application

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Product Information

• Catalog No.: HY-16909
• CAS No.: 87081-35-4
• Molecular Formula: C33H48O6
• Molecular Weight: 540.73
• Purity: 99.79%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (4.62 mM); Clear solution
• Availability: In-stock

Source

Original product source