HDAC6-IN-49

Overview

HDAC6-IN-49 (Compound 3) is an inhibitor for HDAC with IC 50 of 0.012 and 0.735 μM for HDAC6 and HDAC1 . HDAC6-IN-49 also exhibits inhibitory activities against MAO-B , cholinesterase (ChE) , histamine receptor (H3R) and serotonin 6 receptor (5-HT6R) . HDAC6-IN-49 exhibits neuroprotective efficacy on SH-SY5Y cell. HDAC6-IN-49 improves cognitive function and locomotor ability in Drosophila Parkinson's disease models and in C. elegans Alzheimer's disease models.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Histamine Receptor | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-169156
• CAS No.: 3060094-54-1
• Molecular Formula: C23H27N3O5S
• Molecular Weight: 457.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source