RORγ/DHODH-IN-2

Overview

RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC 50 values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC 50 values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Dihydroorotate Dehydrogenase | Products > Signaling Pathways > ROR | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-169222S
• CAS No.: 3000567-45-0
• Molecular Formula: C22H16D2ClF4N5O2
• Molecular Weight: 497.87
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source