Yakuchinone B is an Acyl-CoA: cholesterol O-acyltransferase ( ACAT ) inhibitor with hypocholesterolemic activity, which is found in the seeds of Zingiberaceae . Yakuchinone B inhibits rat hepatic ACAT with an IC 50 value of 20.6 μM. Yakuchinone B is promising for research of hypercholesterolemia and atherosclerosis.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Acyltransferase
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