HDM-IN-1

Overview

HDM-IN-1 (Compound A4) is an inhibitor for fungal histone demethylase ( HDM ), that inhibits the H3K27me3 in Cryptococcus neoformans and in Candida auris with IC 50 s of 134 and 12 nM. HDM-IN-1 exhibits inhibitory efficacy against C. neoformans and C. auris with MIC 80 of 0.5-2 μg/mL, through inhibition of the biofilm and capsule formation. HDM-IN-1 exhibits antifungal activity in ICR mouse model.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Histone Demethylase | Products > Signaling Pathways > Fungal

Product Information

• Catalog No.: HY-169919
• CAS No.: 3020690-76-7
• Molecular Formula: C17H15N5O
• Molecular Weight: 305.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source