Tyk2-IN-22-d 3

Overview

Tyk2-IN-22 -d3 (Compound 1) is the deuterated analog of Tyk2-IN-22 ( HY-168339 ). Tyk2-IN-22 (Compound A8) is a selective inhibitor for tyrosine kinase 2 ( Tyk2 ), that it inhibits Tyk2 , JAK1 , and JAK3 with IC 50 s of 9.7, 148.6, and 883.3 nM, respectively. Tyk2-IN-22 inhibits the downstream STAT5 phosphorylation.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > STAT | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-169984S
• CAS No.: 1771691-32-7
• Molecular Formula: C20H19D3N8O3
• Molecular Weight: 425.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source