PROTAC SMARCA2/4 degrader-36

Overview

PROTAC SMARCA2/4 degrader-36 (Compound 29) is an effective dual degrader of SMARCA2/4 ,with DC 50 values of 0.22 nM and 0.85 nM for SMARCA2 and SMARCA4 , respectively. PROTAC SMARCA2/4 degrader-36 has anti-cell proliferation activity. (Pink: SMARCA2 and SMARCA4 ligand ( HY-170354 ); Blue: VHL ligand ( HY-170353 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-170347
• CAS No.: 3033588-00-7
• Molecular Formula: C53H62ClN9O4S
• Molecular Weight: 956.64
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source