NLRP3-IN-60

Overview

NLRP3-IN-60 (Compound 39) is the orally active inhibitor for NLRP3 . NLRP3-IN-60 inhibits pyroptosis with an IC 50 of 13 nM in THP-1 cell. NLRP3-IN-60 inhibits IL-1β release with an IC 50 of 225 nM in human whole blood.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Pyroptosis

Product Information

• Catalog No.: HY-170364
• CAS No.: 3098827-88-1
• Molecular Formula: C23H24F2N4O4S
• Molecular Weight: 490.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source