SAL-0010042

Overview

SAL-0010042 is the inhibitor for Plasmodium phosphodiesterase β ( PDEβ ), that inhibits the hydrolysis of cAMP and cGMP ( IC 50 =48.9 nM) in gametocytes, activates PKG , and inhibits the growth and development of Plasmodium ( IC 50 for 3D7 and Dd2 is 142 nM and 218 nM). SAL-0010042 inhibits hPDE5 and hPDE6 with IC 50 of 632 nM and 73 nM.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-170431
• CAS No.: 521298-46-4
• Molecular Formula: C15H15FN4O
• Molecular Weight: 286.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source