GSK-3β inhibitor 23

Overview

GSK-3β inhibitor 23 (Compound 11726169) is the inhibitor for glycogen synthase kinase-3 , that inhibits GSK-3β and GSK-3α with IC 50 of 12.1 nM and 18.8 nM. GSK-3β inhibitor 23 exhibits antiviral activity against HIV 1 . GSK-3β inhibitor 23 exhibits good metabolic stablility in mouse/human liver microsomes and plasma, but poor Caco-2 permeability (which predicts low oral bioavailability).

Application

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Product Information

• Catalog No.: HY-170491
• CAS No.: 3116731-08-6
• Molecular Formula: C18H13Cl2N5O2S
• Molecular Weight: 434.30
• Purity: 99.88%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source