NLRP3-IN-61 (Compound 1) is an inhibitor for NLRP3 . NLRP3-IN-61 inhibits pyroptosis in THP-1 cell with an IC 50 of 12.6 nM, inhibits IL-β release with an IC 50 of 25.3 nM.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Pyroptosis
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