SNT-5382

Overview

SNT-5382 is a lysyl oxidase family (LOX) inhibitor and anti-fibrotic agent. SNT-5382 binds to the LTQ cofactor of LOXL2 and inhibits the enzymatic activities of LOXL3 , LOXL4 , LOXL1 , CYP2C9 , and CYP2C19 . SNT-5382 reduces cardiac and liver fibrosis as well as collagen crosslinks, and improves cardiac function. SNT-5382 can be used for the research of heart failure, myocardial infarction, and nonalcoholic steatohepatitis-related liver fibrosis.

Application

Products | Products > Disease Areas > Hepatic Fibrosis | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Disease | Products > Disease Areas > Heart Disease | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Lysyl Oxidase | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-170538
• CAS No.: 2125956-92-3
• Molecular Formula: C20H24Cl2FN3O2S
• Molecular Weight: 460.39
• Purity: 99.93%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.25 mg/mL (2.72 mM); Clear solution
• Availability: In-stock

Source

Original product source