HP211206

Overview

HP211206 is a SARS-CoV-2 main protease ( M pro ) PROTAC degrader. HP211206 effectively degrades SARS-CoV-2 M pro and its drug-resistant mutants. HP211206 has an IC 50 of 181.9 nM and a DC 50 of 621 nM for M pro . HP211206 has antiviral activity. (Pink: SARS-CoV-2 Mpro ligand ( HY-170599 ); Blue: Cereblon ligand ( HY-41547 ); Black: linker ( HY-B0236 )).

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-170598
• CAS No.: 3119106-17-8
• Molecular Formula: C42H55F2N9O10
• Molecular Weight: 883.94
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source