PROTAC XPO1 degrader-1

Overview

PROTAC XPO1 degrader-1 is an XPO1 degrader. PROTAC XPO1 degrader-1 exhibits anti-proliferative effects, can induce cell apoptosis , inhibit NF-κB activity, and cause cell cycle arrest in the G1 phase. PROTAC XPO1 degrader-1 can be used in research on hematological malignancies. (Pink: CRM1 ligand ( HY-170672 ); Blue: Ligands for E3 Ligase ligand ( HY-170671 ); Black: linker ( HY-W010525 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > CRM1

Product Information

• Catalog No.: HY-170669
• CAS No.: 3105680-00-7
• Molecular Formula: C33H35ClF3N7O7
• Molecular Weight: 734.12
• Purity: 99.77%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (3.41 mM); Clear solution
• Availability: In-stock

Source

Original product source