AMPK activator 16 (compound 6) is a AMP-activated protein kinase ( AMPK ) inhibitor. AMPK activator 16 shows the most efficient interactions with the key residues of AMPK and demonstrates significant activation of AMPK . AMPK activator 16 increases the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC ( Acetyl-CoA Carboxylase ) (p-ACC) and phosphorylated raptor (p-raptor), in N2a cells.
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