STING-IN-11 (Compound 42) is an orally active STING inhibitor with an IC 50 of 37.8 nM. STING-IN-11 can block the palmitoylation of the STING protein and STING downstream signaling, and inhibit STING -mediated inflammation. STING-IN-11 has good in vivo safety and can be used for the research of STING -related inflammatory and autoimmune diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > STING | Products > Signaling Pathways > Interleukin Related
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