MS910

Overview

MS910 is an efficient and selective MEK1/2 PROTAC degrader. MS910 exhibits effective MEK1/2 degradation ability and anti proliferative activity in various cancer cells, such as HT-29 ( MEK1 DC 50 = 118 nM, MEK2 DC 50 = 55 nM) and SK-MEL-28 ( MEK1 DC 50 = 94 nM, MEK2 DC 50 = 38 nM) cells. MS910 is commonly used in cancer research. (Pink: MEK1/2 Ligand ( HY-10254 ); Blue: CRBN Ligand ( HY-W087383 ); Black: Linker ( HY-W022240 )) (Pink: MEK1 and MEK2 ligand ( HY-10254 ); Blue: Cereblon ligand ( HY-W087383 ); Black: linker ( HY-W022240 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > MEK

Product Information

• Catalog No.: HY-170982
• CAS No.: 2756323-28-9
• Molecular Formula: C41H48F3IN6O11
• Molecular Weight: 984.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source