SC-919

Overview

SC-919 is an orally active IP6K inhibitor, with an IC 50 of < 5.2 nM against IP6K1 , < 3.8 nM against IP6K2 , and 0.65 nM against IP6K3 . By inhibiting the activity of IP6K, SC-919 reduces intracellular IP7 levels, thereby suppressing XPR1-mediated cellular phosphate efflux. SC-919 increases intracellular phosphate and ATP levels while reducing phosphate entry into the bloodstream, thus decreasing plasma phosphate levels. SC-919 can be used in research related to chronic kidney disease and hyperphosphatemia.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Renal Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > IPK Superfamily

Product Information

• Catalog No.: HY-171099
• CAS No.: 2245949-62-4
• Molecular Formula: C19H16Cl2N2O4
• Molecular Weight: 407.25
• Purity: 98.68%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source