Mal-VC-PAB-DMEA-PNU-159682

Overview

Mal-VC-PAB-DMEA-PNU-159682 (SET0568) is an antibody-drug conjugate (ADC) drug-linker conjugate . Mal-VC-PAB-DMEA-PNU-159682 is generated by conjugating the potent anti- topoisomerase II inhibitor PNU-159682 ( HY-16700 ) to the lysosomally cleavable dipeptide Mc-VC-PAB, and exhibits strong antitumor activity. Mal-VC-PAB-DMEA-PNU-159682 can be used to synthesize CD22 -targeting ADCs, such as Anti-CD22-NMS249 (HY-164761). Mal-VC-PAB-DMEA-PNU-159682 is also applicable to the research of non-Hodgkin's lymphoma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Drug-Linker Conjugates for ADC

Product Information

• Catalog No.: HY-171138
• CAS No.: 1178887-17-6
• Molecular Formula: C66H83N9O22
• Molecular Weight: 1354.41
• Purity: 99.36%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source