SMARt751

Overview

SMARt751 targets the transcriptional regulatory factor VirS , inhibits its DNA binding ability, upregulates the mymA operon expression, thereby activating Ethionamide ( HY-B0276 ), enhancing the antimicrobial activity of Ethionamide . SMARt751 enhances the antibacterial activity of Ethionamide against M. tuberculosis , reverses the Ethionamide resistance. SMARt751 improves the antibacterial effect of Ethionamide and reduces its effective dose in mouse models.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-171317
• CAS No.: 1616370-52-5
• Molecular Formula: C15H17F4NO
• Molecular Weight: 303.30
• Purity: 99.99%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source