3′-Azido-2′,3′-dideoxy-CTP

Overview

3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC 50 values of 15.6 μM and 160.8 μM for WT HIV and AZT R HIV . 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > HIV | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-171574
• CAS No.: 92562-77-1
• Molecular Formula: C9H15N6O12P3
• Molecular Weight: 492.17
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source