SIK2-IN-3

Overview

SIK2-IN-3 is an orally active SIK1/2 selective inhibitor ( IC 50 : 0.128/0.084 μM). SIK2-IN-3 inhibits CRTC3 phosphorylation and myeloid cell pro-inflammatory cytokine production. SIK2-IN-3 ameliorates systemic and tissue inflammatory responses in a mouse anti-CD40 colitis model.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Salt-inducible Kinase (SIK)

Product Information

• Catalog No.: HY-171590
• CAS No.: 2810809-10-8
• Molecular Formula: C23H24N6O2
• Molecular Weight: 416.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source