GLP-1R modulator-1 (Compound 384) is an orally active, potent selective glucagon-like peptide-1 receptor ( GLP-1R ) agonist. GLP-1R modulator-1 activates G-protein coupled signaling, elevates intracellular cAMP levels, promotes insulin secretion, delays gastric emptying and suppresses appetite. GLP-1R modulator-1 is promising for research of type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).
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