BI-9740

Overview

BI-9740 is an orally active and selective cathepsin C ( CatC ) inhibitor, with an IC 50 of 0.6 nM in mice and 2.6 nM in rats. BI-9740 can inhibit the production of active neutrophil elastase . Additionally, BI-9740 is capable of reducing the activities of neutrophil elastase and cathepsin G in the bone marrow of rats, alleviating pathological damage to grafts after heart transplantation, shortening the reperfusion time, and improving left ventricular function. BI-9740 can be used in research related to organ transplantation.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cathepsin | Products > Signaling Pathways > Elastase

Product Information

• Catalog No.: HY-171888
• CAS No.: 1628596-25-7
• Molecular Formula: C25H25FN4O2
• Molecular Weight: 432.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source