5β-Cholestane-3α,7α,12α,25-tetrol

Overview

5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) is a bile acid alcohol. 5β-Cholestane-3α,7α,12α,25-tetrol is a GPBAR1 (also known as TGR5 ) activator ( EC 50 : 1.36 μM). 5β-Cholestane-3α,7α,12α,25-tetrol is the predominant bile-alcohol disease marker present in patients with Cerebrotendinous xanthomatosis (CTX).

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > G protein-coupled Bile Acid Receptor 1 | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-171949
• CAS No.: 18866-87-0
• Molecular Formula: C27H48O4
• Molecular Weight: 436.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source