ONO-2920632

Overview

ONO-2920632 is an orally active and central nervous system (CNS)-penetrant TREK activator, with EC 50 values of 0.3 µM and 2.8 μM for TREK-1 and TREK-2 , respectively. ONO-2920632 exhibits selectivity for other K2P channels (>91-fold selective versus TASK1, TASK2, TASK3, TRAAK, and TWIK2; 31-fold selective versus TRESK). ONO-2920632 possesses analgesic effects and can be used in research on pain, migraine, and neurological disorders.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-172182
• CAS No.: 2230296-66-7
• Molecular Formula: C15H10F4N4O2
• Molecular Weight: 354.26
• Purity: 99.11%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (14.11 mM); Clear solution
• Availability: In-stock

Source

Original product source