S-15176

Overview

S-15176 is an inhibitor of the mitochondrial permeability transition pore ( PTP ). S-15176 inhibits mitochondrial swelling induced by tert-butylhydroperoxide with an IC 50 value of 45.7 μM. S-15176 inhibits PTP opening, prevents mitochondrial membrane potential dissipation and NAD(P)H oxidation, and increases mitochondrial calcium loading capacity. S-15176 is promising for research of ischemia-reperfusion injury.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

• Catalog No.: HY-172227
• CAS No.: 148089-70-7
• Molecular Formula: C31H48N2O4S
• Molecular Weight: 544.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source