NBTI 5463

Overview

NBTI 5463 is a bacterial type II topoisomerases ( topoisomerase II ) inhibitor with antibacterial activity. NBTI 5463 inhibits GyrA and TopoIV in Pseudomonas aeruginosa and Escherichia coli . NBTI 5463 binds to topoisomerase II to prevent DNA cleavage and religation, inhibiting bacterial DNA replication and transcription. NBTI 5463 is promising for research of Gram-negative bacterial infection .

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-172229
• CAS No.: 1227303-03-8
• Molecular Formula: C25H30N6O4
• Molecular Weight: 478.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source