SDH-IN-25

Overview

SDH-IN-25 is a succinate dehydrogenase (SDH) inhibitor ( IC 50 = 4.82 mg/L). SDH-IN-25 exhibited broad-spectrum and potent antifungal activity. SDH-IN-25 mimics the interaction pattern of commercial fungicide Fluxapyroxad ( HY-135549 ) through binding to SDH amino acid residues (TRP173, TYR58, and ARG43). SDH-IN-25 can induce hyphal morphology, interfere with respiratory metabolism by binding to complex II, generate reactive oxygen species (ROS) , and affect mitochondrial membrane potential ( MMP ) in mycelia. SDH-IN-25 can be studied in research for agricultural disease control.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Signaling Pathways > Succinate Dehydrogenase | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-172777
• CAS No.: 3052432-15-9
• Molecular Formula: C19H15BrCl2N2O4
• Molecular Weight: 486.14
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source