SP11

Overview

SP11 is a mitochondrial fission protein 1 ( Fis1) inhibitor with an IC 50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinson’s disease.

Application

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Product Information

• Catalog No.: HY-172942
• CAS No.: 2629218-24-0
• Molecular Formula: C18H19ClN2OS
• Molecular Weight: 346.87
• Purity: 98.91%
• Storage: Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source