SD-2301

Overview

SD-2301 is a selective STAT3 PROTAC degrader. SD-2301 induces STAT3 degradation without affecting the protein levels of other STAT family members ( STAT1 , STAT2, STAT4, STAT5 , STAT6 ). SD-2301 exerts anti-tumor effects in B16F10-bearing mice. SD-2301 can be used for the study of cancer . (Pink: STAT3 ligand ( HY-172947 ); Blue: VHL ligand ( HY-112078 ); Black: linker ( HY-W577012 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > STAT

Product Information

• Catalog No.: HY-172946
• CAS No.: 3054116-24-1
• Molecular Formula: C64H80N13O15PS2
• Molecular Weight: 1366.50
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (1.83 mM); Clear solution
• Availability: In-stock

Source

Original product source