PROTAC SMARCA2/4 degrader-38

Overview

PROTAC SMARCA2/4 degrader-38 is a degrader SMARCA2/4 PROTAC (DC 50 : 3.0 nM and 4.0 nM respectively). PROTAC SMARCA2/4 degrader-38 promotes the ubiquitination and degradation of SMARCA2/4. PROTAC SMARCA2/4 degrader-38 blocks the G0/G1 cell cycle and induces apoptosis . PROTAC SMARCA2/4 degrader-38 can be used in acute myeloid leukemia (AML) research. (Pink: Target protein ligand; Blue: VHL ligand ( HY-112078 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-173333
• CAS No.: 3081688-77-6
• Molecular Formula: C43H47N7O5S
• Molecular Weight: 773.94
• Purity: 99.46%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source