GLP-1R agonist 30

Overview

GLP-1R agonist 30 is a selective and orally active GLP-1R agonist with an EC 50 of 0.048 nM. GLP-1R has excellent selectivity, with EC 50 greater than 20 μM for GLP-2R, GIPR, and GCPR. GLP-1R agonist significantly increases cAMP-stimulating activity while markedly reducing hERG inhibitory activities. GLP-1R agonist has preferable absorption and excellent β-arrestin pathway selectivity. GLP-1R agonist effectively improves glucose tolerance and promoted insulin secretion in B-hGLP1R knock-in mice.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-173479
• CAS No.: 3108380-54-4
• Molecular Formula: C33H32F3N5O4
• Molecular Weight: 619.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source