CC-647

Overview

CC-647 is a molecular glue modulator targeting Cereblon (CRBN) E3 ubiquitin ligase . CC-647 promotes the interaction between CRBN and ZBTB16 as well as its oncogenic fusion protein RARα-ZBTB16 (with a DC 50 of 103 nM). CC-647 is promising for research of ZBTB16-RARα-associated acute promyelocytic leukemia (APL).

Application

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Product Information

• Catalog No.: HY-173614
• CAS No.: 1061605-35-3
• Molecular Formula: C23H22N2O5
• Molecular Weight: 406.43
• Purity: 99.58%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source