Dimethyl fumarate

Overview

Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ ROS increase/MAPKs activation pathway, and also induces cell autophagy . Dimethyl fumarate can be used for multiple sclerosis research.

Application

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Product Information

• Catalog No.: HY-17363
• CAS No.: 624-49-7
• Molecular Formula: C6H8O4
• Molecular Weight: 144.13
• Purity: 99.99%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 3.33 mg/mL (23.10 mM); Clear solution
• Availability: In-stock

Source

Original product source