(S)-dHTC1

Overview

(S)-dHTC1 is a molecular glue degrader targeting the transcriptional co-activator ENL . (S)-dHTC1 binds the ligase with high affinity only after forming the ENL:dHTC1 complex with an IC 50 value of 93 nM. (S)-dHTC1 degrades ENL in MV4;11 cells with a DC 50 value of 26 nM. (S)-dHTC1 can be used for acute myeloid leukemia study.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-173631
• CAS No.: 3081383-46-9
• Molecular Formula: C33H40N8O6S
• Molecular Weight: 676.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source