Nisoldipine

Nisoldipine
  • CAS No.:63675-72-9
  • Grade:99.56%
  • Formula:C20H24N2O6
  • M.W.:388.41
  • Solvent:≥ 2.5 mg/mL (6.44 mM); Clear solution

Overview

Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels . Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

  • Catalog No.: HY-17402
  • CAS No.: 63675-72-9
  • Molecular Formula: C20H24N2O6
  • Molecular Weight: 388.41
  • Purity: 99.56%
  • Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
  • Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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