Y2641

Overview

Y2641, a etrahydro-β-carboline derivative, is an orally active dual RANKL/TNF-α inhibitor with K d values of 3.984 μM and 18.59 μM for RANKL and TNF-α, respectively. Y2641 inhibits RANKL-induced osteoclastogenic and has anti-inflammatory and cartilage destruction. Y2641 can be used for study of osteoarthritis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > RANKL/RANK | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-174156
• CAS No.: 3092616-03-7
• Molecular Formula: C28H28N4O
• Molecular Weight: 436.55
• Purity: 98.31%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.45 mM); Clear solution
• Availability: In-stock

Source

Original product source