PROTAC PI3K/110β degrader-2

Overview

PROTAC PI3K/110β degrader-2 is a selective PI3K/p110β PROTAC degrader. PROTAC PI3K/110β degrader-2 can significantly degrade 110β protein and inhibit the expression of P-glycoprotein . PROTAC PI3K/110β degrader-2 can increase the level of reactive oxygen species (ROS) . PROTAC PI3K/110β degrader-2 exerts anti-tumor effects by activating the endoplasmic reticulum stress (ERS)-mediated mitochondrial apoptosis pathway and inhibiting the AKT/Bcl-2 signaling pathway. PROTAC PI3K/110β degrader-2 can be used for research on cancer . (Pink: PI3K and p110β ligand ( HY-75124 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-W002042 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > P-glycoprotein | Products > Signaling Pathways > Akt | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Na+/K+ ATPase | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-174469
• CAS No.: 3070438-79-5
• Molecular Formula: C51H65N9O7S
• Molecular Weight: 948.18
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source